Dr Floyd Taub spearheaded several advances in science and medicine. His founding of Digene led to the first and most used DNA test to diagnose and prevent cancer. Cervical cancer is now rare in screened populations. As cervical cancer screening has produced the single greatest decrease in a major cancer, he will be asked: “Is medicine ready for new technologies that can prevent disease?”. He drove into clinical trials the first drug that (indirectly) modulates immune checkpoints and decreases myeloid derived immune suppression. Immune modulation has revolutionized cancer therapy, it is the only accepted therapy that can, unfortunately in too few cases, cure late stage cancer. Recently he has worked to amplify this effect. Immunotherapy may prevent incipient cancers from becoming clinical cancer. He developed the first quantitative image processing analysis of gene expression. He evaluated expression of 10,000 genes simultaneously. With Australian partners, he is now pioneering work on genes and organisms in the vaginal biome that may inhibit heterosexual transmission of HIV and reduce the lifelong medical, emotional and financial trauma of pre-term birth. He trained at Northwestern University (M.D.), University of Colorado (Pathology Residency), George Washington University (Pathology Fellowship) and spent 10 years at NIH in Bethesda.